Document Detail

Clinical and subclinical thiamine deficiency in clinical practice.
MedLine Citation:
PMID:  4042079     Owner:  NLM     Status:  MEDLINE    
Six patients with gross thiamine deficiency found during normal psychiatric practice in England are described. Two surveys of newly admitted psychiatric patients are recounted. A major degree of biochemical deficiency, with or without minimal clinical manifestations, was found. Only three (1%) of 326 patients surveyed had gross clinical deficiency. It is thought that severe thiamine deficiency, though rare in the Western countries, has not been eradicated. Deficiency may cause psychiatric conditions like Wernicke's encephalopathy or may be a secondary feature in mental illness due to anorexia, in reduced food intake, and in poor nutrition. The importance of being aware of the possibility for correct diagnosis is emphasised.
M W Carney; S Barry
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical neuropharmacology     Volume:  8     ISSN:  0362-5664     ISO Abbreviation:  Clin Neuropharmacol     Publication Date:  1985  
Date Detail:
Created Date:  1985-11-13     Completed Date:  1985-11-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607910     Medline TA:  Clin Neuropharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  286-93     Citation Subset:  IM    
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MeSH Terms
Alcoholism / complications
Beriberi / complications
Middle Aged
Thiamine Deficiency / complications,  psychology*
Wernicke Encephalopathy / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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