Document Detail

Clinical study of hemodynamic changes during extraction in controlled hypertensive patients.
MedLine Citation:
PMID:  21196862     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the efficacy and safety of the vasoconstrictor used in local anesthesia during dental extraction in controlled hypertensive patients.
STUDY DESIGN: A prospective observational study was carried out in hypertensive patients (n=97) with a mean age of 60.45±9.60 years. The following parameters were monitored at three different timepoints (before the procedure, 3 minutes after local anesthesia infiltration, and 3 minutes after the operation): blood pressure (diastolic and systolic), heart rate, and oxygen saturation. Anesthesia (1-3 carpules) was provided in the form of articaine with 4% epinephrine as vasoconstrictor in one group, while another group received 3% mepivacaine without vasoconstrictor.
RESULTS: All patients presented primary hypertension (n=97)(grade I in 57.7% of the cases and grade II in 42.3%). The most widely used antihypertensive drugs were angiotensin II receptor antagonists (ARA II). The only significant differences observed corresponded to systolic blood pressure measured before and after dental extraction in the group of hypertensive patients anesthetized with vasoconstrictor.
CONCLUSIONS: In procedures such as dental extraction, no significant hemodynamic changes in well controlled hypertensive patients are seen attributable to anesthetic use with a vasoconstrictor, when fewer than three local anesthetic carpules are administered.
Francisco-Javier Silvestre; Isabel Salvador-Martínez; Daniel Bautista; Javier Silvestre-Rangil
Publication Detail:
Type:  Journal Article     Date:  2011-05-01
Journal Detail:
Title:  Medicina oral, patología oral y cirugía bucal     Volume:  16     ISSN:  1698-6946     ISO Abbreviation:  Med Oral Patol Oral Cir Bucal     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-02     Completed Date:  2011-09-01     Revised Date:  2011-09-14    
Medline Journal Info:
Nlm Unique ID:  101231694     Medline TA:  Med Oral Patol Oral Cir Bucal     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  e354-8     Citation Subset:  D; IM    
Department of Stomatology, Valencia University Dental School, Stomatology Unit, Dr. Peset University Hospital, Juan de Garay s/n, 46017 Valencia, Spain.
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MeSH Terms
Aged, 80 and over
Hypertension / physiopathology*
Intraoperative Period
Middle Aged
Prospective Studies
Tooth Extraction*
Vasoconstrictor Agents / therapeutic use*
Reg. No./Substance:
0/Vasoconstrictor Agents

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