| Clinical status and acid-base balance during biofiltration in patients with acetate dialysis intolerance. | |
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MedLine Citation:
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PMID: 3557662 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nine patients intolerant to acetate hemodialysis were treated with biofiltration. This consisted in a 4-h acetate hemodialysis during which an additional 2 liters of ultrafiltrate were replaced by a bicarbonate solution (100 mEq/l). Hypotensive episodes disappeared and six out of nine patients were symptom-free during the session. Compared to standard hemodialysis, arterial blood bicarbonate and pO2 did not drop during biofiltration. The anion gap did not change during standard hemodialysis, but was significantly reduced during biofiltration (24.5 +/- 2.9 vs 19.9 +/- 1.4 mEq/l). In our conditions clinical results were positive with biofiltration. On the basis of anion gap changes and preliminary results of plasma acetate determinations, it is suggested that a better cellular metabolism of acetate may be induced by bicarbonate infusion. |
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Authors:
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G Panzetta; N Tessitore; E Valvo; A Lupo; C Loschiavo; A Fabris; L Oldrizzi; R Panebianco; C Rugiu; Z Bellotti |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The International journal of artificial organs Volume: 9 Suppl 3 ISSN: 0391-3988 ISO Abbreviation: Int J Artif Organs Publication Date: 1986 Dec |
Date Detail:
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Created Date: 1987-05-11 Completed Date: 1987-05-11 Revised Date: 2006-04-17 |
Medline Journal Info:
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Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: ITALY |
Other Details:
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Languages: eng Pagination: 137-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetates
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administration & dosage Acid-Base Equilibrium* Adult Aged Blood* Blood Chemical Analysis Blood Gas Analysis Cellulose / analogs & derivatives Female Humans Hypotension / prevention & control Membranes, Artificial Middle Aged Renal Dialysis / adverse effects* Ultrafiltration / methods* |
| Chemical | |
Reg. No./Substance:
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0/Acetates; 0/Membranes, Artificial; 9004-34-6/Cellulose; 9050-09-3/cuprammonium cellulose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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