Document Detail


Clinical signs of normal plasma volume expansion during pregnancy.
MedLine Citation:
PMID:  6837676     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A majority of cases of pregnancy complications are associated with a relative maternal hypovolemia. The records of 200 pregnant women who had had plasma volume determinations were reviewed in hopes of finding indicators of relative maternal hypovolemia other than the pregnancy complication itself. The signs of relative hypovolemia in pregnant women include those of decreased uterine growth, absence of a maternal systolic flow murmur, and absence of significant dependent ankle edema. Laboratory tests indicative of maternal hypovolemia include failure to develop a decline in maternal hematocrit, serum blood urea nitrogen/creatinine ratio greater than 15, a decreased creatinine clearance, abnormal platelet function, elevated serum glutamic oxaloacetic transaminase, ultrasonic evidence of oligohydramnios and/or decreased maternal heart size, and absence of hypervolemia on chest x-ray film. These findings and tests are only relative indicators of maternal hypovolemia, and it is suggested that, for an accurate defining of pregnant women who are at risk, the actual plasma volume determination has to be performed frequently in the pregnant population.
Authors:
R C Goodlin; C A Dobry; J C Anderson; R E Woods; M Quaife
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  145     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1001-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Aspartate Aminotransferases / blood
Blood Urea Nitrogen
Body Weight
Creatinine / blood,  urine
Edema / diagnosis
Female
Fetal Growth Retardation / diagnosis
Heart Murmurs
Hematocrit
Humans
Plasma Volume*
Platelet Function Tests
Pregnancy*
Pregnancy Complications / diagnosis*
Retrospective Studies
Ultrasonography
Chemical
Reg. No./Substance:
60-27-5/Creatinine; EC 2.6.1.1/Aspartate Aminotransferases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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