Document Detail


Clinical significance of pulmonary function tests. Pulmonary function after uncomplicated myocardial infarction.
MedLine Citation:
PMID:  891288     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Derangement of pulmonary function following myocardial infarction is related to the severity of hemodynamic dysfunction. Abnormalities of pulmonary function appear even in patients without clinical or radiologic evidence of congestive failure. There is a reduction in vital capacity and rates of air flow. There is evidence for dysfunction of "small airways" and diminished ventilation to dependent parts of the lung. Total lung capacity may be normal or reduced, and residual volume may be increased slightly in uncomplicated myocardial infarction. Residual volume falls with more pronounced pulmonary congestion and edema. Distribution of pulmonary perfusion is altered after myocardial infarction, with a shift of perfusion away from the dependent parts of the lung (bases) towards the apices. Pulmonary gas exchange is impaired, with hypoxemia (due to both ventilation-perfusion inequality and increased shunting); and the diffusing capacity for carbon monoxide is diminished. Dead space is increased. The basic pathophysiologic mechanism responsible for abnormalities of pulmonary function is increased pulmonary water, which may be very minimal with uncomplicated myocardial infarction and stay primarily in the pulmonary interstitial space, but becomes progressively more severe with eventual alveolar flooding and marked impairment of pulmonary function.
Authors:
C A Hales; H Kazemi
Related Documents :
23610578 - Percutaneous coronary intervention in nonagenarians: pros and cons.
24703918 - Use of myocardial strain imaging by echocardiography for the early detection of cardiot...
8786618 - A chronic cardiomyopathy in feedlot cattle attributed to toxic levels of salinomycin in...
14077808 - Effect of an aldosterone antagonist (spironolactone) on patients with severe congestive...
23799628 - Organogenesis of the vertebrate heart.
2405608 - Relationship between antecedent angina pectoris and short-term prognosis after thrombol...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Chest     Volume:  72     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1977 Sep 
Date Detail:
Created Date:  1977-10-28     Completed Date:  1977-10-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  350-8     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Humans
Lung / radiography
Lung Volume Measurements
Myocardial Infarction / physiopathology*
Peak Expiratory Flow Rate
Pulmonary Edema / etiology
Respiratory Function Tests*
Ventilation-Perfusion Ratio

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Aspects of chronic airflow obstruction.
Next Document:  Pulmonary infiltration with eosinophila. Recurrence in an asthmatic patient treated with beclomethas...