Document Detail

Clinical significance of neurofibromatosis in pregnancy.
MedLine Citation:
PMID:  8579663     Owner:  NLM     Status:  MEDLINE    
Neurofibromatosis (NF) is a common genetic disease that affects multiple organ systems. We studied eight women with NF and the outcome of their 14 pregnancies. One patient and her fetus died of a massive intracranial hemorrhage as a result of ruptured glioblastoma of the basal ganglia. The incidence of live birth and preterm labor were 50% and 28.6%, respectively. One of 14 pregnancies (7.1%) resulted in spontaneous abortion. There was also one growth-retarded fetus in this series (7.1%). Perinatal implications of this disease and management guidelines are discussed.
H A Hadi
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of perinatology     Volume:  12     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-03-20     Completed Date:  1996-03-20     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  459-61     Citation Subset:  IM    
Department of Obstetrics and Gynecology, East Carolina University School of Medicine, Greenville, North Carolina 27858, USA.
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MeSH Terms
Fetal Death
Infant, Newborn
Neurofibromatoses / complications*
Pregnancy Complications, Neoplastic*
Pregnancy Outcome*

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