Document Detail


Clinical significance of intestinal type fatty acid binding protein in patients undergoing coronary artery bypass surgery.
MedLine Citation:
PMID:  21821499     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: The aim of this study was to determine whether serum levels of intestinal type fatty acid binding protein (I-FABP) are related to intestinal ischemia in patients undergoing coronary bypass surgery. METHODS: The study was planned as prospective, observational. Elective coronary artery bypass candidate patients between ages of 50 and 70 were consecutively included in the study. Thirty-five patients scheduled for cardiopulmonary bypass (CPB) were identified as the CPB group and 16 patients not scheduled for CPB were identified as the off-pump coronary artery bypass surgery (OPCAB) group. The variables between and within the groups were analyzed with Student's t, Mann-Whitney U, Friedman and Wilcoxon tests respectively. RESULTS: In both CPB and OPCAB groups, I-FABP level at the end of the operation was significantly higher than that noted at the beginning of the operation (p<0.005). In the CPB group, there was a significant drop in I-FABP from the end of the operation to each of the postoperative time points (12th hour and 24th hour) (respectively p<0.001, p<0.001). In the OPCAB group, the I-FABP levels at both postoperative time points were lower than that at the end of the operation (p<0.001), and the level at 24-hour post-surgery was significantly lower than at both the end-of-operation I-FABP value (p<0.001) and the 12-hour post-surgery I-FABP value. CONCLUSION: Since we have not observed any intestinal ischemia through our research, slight changes of I-FABP measurements make us believe that I-FABP would be a valuable way to monitor for intestinal ischemia in patients who undergo cardiac surgery.
Authors:
Aynur Camkıran; Aslı Dönmez; Derya Aldemir; Rauf Agah Işgüzar; Bahadır Gültekin
Related Documents :
19147419 - The orbicularis oculi muscle flap: its use for treatment of lagophthalmos and a review ...
7817889 - Copious lactation following augmentation mammaplasty: an uncommon but not rare condition.
24728779 - Adjacent segment degeneration and disease after lumbar fusion compared with motion-pres...
19160429 - Antiestrogen therapy for hereditary hemorrhagic telangiectasia: a double-blind placebo-...
24757479 - Radiologic changes of anterior cervical discectomy and fusion using allograft and plate...
7568479 - Transconjunctival versus transcutaneous lower eyelid blepharoplasty: a prospective study.
19380549 - Radiologist-supervised ketamine sedation for solid organ biopsies in children and adole...
8604459 - Intrathecal infusion systems for treatment of chronic low back and leg pain of noncance...
22551909 - Combination therapy with warfarin plus clopidogrel improves outcomes in femoropopliteal...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-8
Journal Detail:
Title:  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology     Volume:  -     ISSN:  1308-0032     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101095069     Medline TA:  Anadolu Kardiyol Derg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Anesthesiology, Faculty of Medicine, Başkent University, Ankara-Turkey. acamkiran@gmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical outcomes of mitral valve repair in mitral regurgitation: a prospective analysis of 100 cons...
Next Document:  The effect of streptokinase therapy in STEMI and conventional therapy in NSTEMI patients on TIMI ris...