Document Detail

Clinical significance of gastric juice viscosity in peptic ulcer patients.
MedLine Citation:
PMID:  3409793     Owner:  NLM     Status:  MEDLINE    
We developed a simple method of determining gastric juice viscosity using a cone plate viscometer and tested its clinical application in the staging of peptic ulcers. We found a significant positive correlation between viscosity and macromolecular glycoprotein concentration of gastric juice (P less than 0.001). Gastric juice viscosity in active and healing gastric ulcer patients was significantly lower than that in the scarring stage or hospital control patients (P less than 0.05 and P less than 0.01, respectively). In duodenal ulcer patients, a significant difference was found between the active and healing stages and hospital controls (P less than 0.01). However, the difference between the active and healing stages and the scarring stage was not significant. Gastric juice viscosity is a simple, reliable, clinically useful measure.
Y Kurita; S Nakazawa; K Segawa; Y Tsukamoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  33     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-10-06     Completed Date:  1988-10-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1070-6     Citation Subset:  AIM; IM    
Second Department of Internal Medicine, Nagoya University School of Medicine, Japan.
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MeSH Terms
Duodenal Ulcer / metabolism,  physiopathology*
Gastric Juice / analysis*
Glycoproteins / analysis*
Hexoses / diagnostic use
Middle Aged
Saliva / analysis
Stomach Ulcer / metabolism,  physiopathology*
Reg. No./Substance:
0/Glycoproteins; 0/Hexoses

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