Document Detail


Clinical significance of creative 3D-image fusion across multimodalities [PET+CT+MR] based on characteristic coregistration.
MedLine Citation:
PMID:  22260897     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To investigate a registration approach for 2-dimension (2D) based on characteristic localization to achieve 3-dimension (3D) fusion from images of PET, CT and MR one by one. METHOD: A cubic oriented scheme of"9-point & 3-plane" for co-registration design was verified to be geometrically practical. After acquisiting DICOM data of PET/CT/MR (directed by radiotracer (18)F-FDG etc.), through 3D reconstruction and virtual dissection, human internal feature points were sorted to combine with preselected external feature points for matching process. By following the procedure of feature extraction and image mapping, "picking points to form planes" and "picking planes for segmentation" were executed. Eventually, image fusion was implemented at real-time workstation mimics based on auto-fuse techniques so called "information exchange" and "signal overlay". RESULT: The 2D and 3D images fused across modalities of [CT+MR], [PET+MR], [PET+CT] and [PET+CT+MR] were tested on data of patients suffered from tumors. Complementary 2D/3D images simultaneously presenting metabolic activities and anatomic structures were created with detectable-rate of 70%, 56%, 54% (or 98%) and 44% with no significant difference for each in statistics. CONCLUSION: Currently, based on the condition that there is no complete hybrid detector integrated of triple-module [PET+CT+MR] internationally, this sort of multiple modality fusion is doubtlessly an essential complement for the existing function of single modality imaging.
Authors:
Matthew Jian-Qiao Peng; Xiangyang Ju; Balvinder S Khambay; Ashraf F Ayoub; Chin-Tu Chen; Bo Bai
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-17
Journal Detail:
Title:  European journal of radiology     Volume:  -     ISSN:  1872-7727     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Crown Copyright © 2012. Published by Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Joint Surgery @ 1st Affiliated Hospital of Guangzhou Medical College & Orthopedic implantation key lab of Guangdong Province, China.
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