Document Detail

Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction.
MedLine Citation:
PMID:  12122607     Owner:  NLM     Status:  MEDLINE    
This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-beta-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction (DeltaEF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the DeltaEF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r =.63, P <.001; r =.74, P <.001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI.
Satoshi Isobe; Mitsuhiro Okada; Akitada Ando; Mamoru Nanasato; Makoto Nonokawa; Hideo Izawa; Takahisa Kondo; Makoto Hirai; Mitsuhiro Yokota; Yoshifumi Tanahashi; Hidehiko Saito
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  35     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-07-17     Completed Date:  2002-10-17     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  173-80     Citation Subset:  IM    
Division of Cardiology, First Department of Internal Medicine, Nagoya University Graduate School of Medicine, Japan.
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MeSH Terms
Fatty Acids / diagnostic use
Iodobenzenes / diagnostic use
Middle Aged
Myocardial Infarction / physiopathology*
Thallium Radioisotopes / diagnostic use
Tomography, Emission-Computed, Single-Photon
Reg. No./Substance:
0/Fatty Acids; 0/Iodobenzenes; 0/Thallium Radioisotopes; 116754-87-1/iodofiltic acid

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