| Clinical scoring system in the evaluation of adult pharyngitis. | |
| | |
MedLine Citation:
|
PMID: 8435167 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To compare results of a clinical scoring system for diagnosis of group A streptococcal pharyngitis with microbiologic results, when several different pharyngeal pathogens were tested simultaneously. DESIGN: Evaluation of clinical manifestations of 106 adult patients with pharyngitis of different microbial origin. SETTING: General private practice; Health Center Pulssi, Turku, Finland. PATIENTS: Adult patients whose chief complaints were sore throats. MAIN OUTCOME MEASURE: A symptom score that was assigned to each patient according to the total number of certain signs and symptoms that are postulated to increase the probability of group A streptococcal pharyngitis and blood measurements for infection. RESULTS: The highest symptom scores, 3 and 4, were found in 21 patients. These patients had pharyngitis due to group A streptococcus (four patients), group C streptococcus (four patients), group G streptococcus (two patients), group F streptococcus, Mycoplasma pneumoniae, Chlamydia pneumoniae, influenza A virus, influenza B virus, herpes simplex type 1 virus (two patients), and coxsackie B4 virus. No pathogen could be identified from three of the 21 patients. The C-reactive protein values and the leukocyte counts were raised significantly more often in streptococcal infections than in infections of other origin; the P values were .00016 and .028, respectively. CONCLUSION: Use of a clinical scoring system alone for diagnosis of pharyngitis may lead to improper use of anti-microbial agents. There is a need for accurate microbiologic diagnostic procedures in general practice to determine proper treatment of pharyngitis as well as to test the effect of antibacterial and, in the future, antiviral treatment in respiratory tract infections. |
| | |
Authors:
|
H Sepp?l?; R Lahtonen; T Ziegler; O Meurman; K Hakkarainen; A Miettinen; P Arstila; J Eskola; P Saikku; P Huovinen |
Related Documents
:
|
18043447 - Unexpected individual clinical site variation in eradication rates of group a streptoco... 2110537 - Double-blind, placebo-controlled multicentre trial of the efficacy and tolerance of mor... 18831297 - Ventilator-associated pneumonia: problems with diagnosis and therapy. 16978077 - Comparison of sequential intravenous/oral ciprofloxacin plus metronidazole with intrave... 16553907 - Predicting the clinical outcome of tetanus: the tetanus severity score. 20488837 - Sensitivity designs for preventing bias replication in randomized clinical trials. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Archives of otolaryngology--head & neck surgery Volume: 119 ISSN: 0886-4470 ISO Abbreviation: Arch. Otolaryngol. Head Neck Surg. Publication Date: 1993 Mar |
Date Detail:
|
Created Date: 1993-03-25 Completed Date: 1993-03-25 Revised Date: 2010-03-24 |
Medline Journal Info:
|
Nlm Unique ID: 8603209 Medline TA: Arch Otolaryngol Head Neck Surg Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 288-91 Citation Subset: AIM; IM |
Affiliation:
|
Antimicrobial Research Laboratory, National Public Health Institute, Turku, Finland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult C-Reactive Protein / analysis Evaluation Studies as Topic Female Humans Leukocyte Count Male Middle Aged Pharyngitis / blood, diagnosis*, microbiology Predictive Value of Tests Pregnancy Pregnancy Complications, Infectious / diagnosis Streptococcal Infections / blood, diagnosis* Streptococcus pyogenes* |
| Chemical | |
Reg. No./Substance:
|
9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of inhalant anesthesia on the middle ear as measured by tympanometry.
Next Document: Control of early postoperative pain with bupivacaine in adult local tonsillectomy.