Document Detail

Clinical and scintigraphic comparison of silicone and polyvinylpyrrolidone coated silicone perforated plugs.
MedLine Citation:
PMID:  9930274     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIM: Isolated stenosis of the lacrimal punctum is a frequent cause of epiphora. Treatment relies on surgical opening or dilatation with bi- or monocanalicular prosthesis. Recently, silicone perforated punctum plugs (PPP) were proposed. The drawback with these silicone PPP was that secretions accumulate in the central orifice blocking the spontaneous flow of tears. A modification of the surface of the PPP using polyvinylpyrrolidone (PVP) was thus proposed. The aim was to compare silicone PPP with new PVP surface treated PPP. METHODS: A prospective study was conducted of 20 patients with dilatable stenosis of the lacrimal puncta who developed epiphora. Epiphora, tolerance, implantation of the PPP, and lacrimal drainage were evaluated using scintigraphy of the lacrimal ducts. RESULTS: The raw data and statistical analysis showed evidence of a superior performance of PVP surface treated PPP. CONCLUSION: Long term evaluation of the advantages or risks of PVP plugs and comparison with microsurgical punctoplasty are warranted.
T Malet; B Challier; N David; A Bertrand; J L George
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  82     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-02-22     Completed Date:  1999-02-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1416-9     Citation Subset:  IM    
Service d'Ophtalmologie, Centre Hospitalier Universitaire de Nancy, France.
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MeSH Terms
Drainage / instrumentation
Lacrimal Apparatus Diseases / radionuclide imaging,  therapy*
Lacrimal Duct Obstruction / radionuclide imaging,  therapy
Povidone / therapeutic use*
Prospective Studies
Prostheses and Implants
Silicone Elastomers / therapeutic use*
Single-Blind Method
Treatment Outcome
Reg. No./Substance:
0/Silicone Elastomers; 9003-39-8/Povidone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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