Document Detail


Clinical results of coronary excimer laser angioplasty: report from the European Coronary Excimer Laser Angioplasty Registry.
MedLine Citation:
PMID:  8174589     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
From January 1991 to January 1993 the clinical and angiographic data of 470 patients were included in the European Coronary Excimer Laser Angioplasty Registry. Symptoms were CCS class 3 in 23% and CCS class 4 in 14.7%; unstable angina was present in 14.7% and 6.6% of patients had acute myocardial infarction. Of 477 treated lesions, 60% were type B2, and 19% type C. The lesion was located in the LAD in 61%, in the LCX in 16%, in the RCA in 20%, in a protected left main stem in 1.3% and in a saphenous vein graft in 2.5%, respectively. Failure of laser angioplasty occurred in 56 (12%) interventions. By multivariate analysis failure was associated with the intention to treat long segmental lesions (risk ratio (RR) 3.6, confidence interval (CI) 2.9 to 4.4; P = 0.0005), segments with severe prestenotic tortuosity (RR 3.5, CI 2.4 to 4.6; P = 0.02) and total occlusions (RR 2.1; CI 1.4 to 2.8; P = 0.05). Complications included vasospasm (13.4%), dissection (14.7%), flow limiting dissection (4%), reclosure (7.8%), and perforation (1.9%). Myocardial infarction occurred in 2.1%, CABG was requested in 1.9%, and the mortality was 1.5%. Procedural success was achieved in 89%. Individual morphological criteria for a reduced procedural success were the presence of a thrombus (RR 6.4; CI 5.0 to 7.7; P = 0.007) and vessel calcification (RR 2.6; CI 1.9 to 3.2; P = 0.005). Procedural success was slightly lower in type C lesions (86%) than in type B2 (88%) type B1 (95%), and type A lesions (92%), respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
A Baumbach; H Oswald; J Kvasnicka; E Fleck; H J Geschwind; C Ozbek; N Reifart; M E Bertrand; K R Karsch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European heart journal     Volume:  15     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1994 Jan 
Date Detail:
Created Date:  1994-06-07     Completed Date:  1994-06-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  89-96     Citation Subset:  IM    
Affiliation:
Medizinische Klinik III, University of Tübingen, Germany.
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MeSH Terms
Descriptor/Qualifier:
Angioplasty, Balloon, Laser-Assisted / adverse effects,  statistics & numerical data*
Angioplasty, Transluminal, Percutaneous Coronary / methods*
Coronary Disease / epidemiology,  surgery*
Europe
Female
Humans
Male
Middle Aged
Multicenter Studies as Topic
Multivariate Analysis
Registries / statistics & numerical data*
Treatment Failure
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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