Document Detail

Clinical resolution of a neonatally eroded giant congenital melanocytic nevus.
MedLine Citation:
PMID:  17156000     Owner:  NLM     Status:  MEDLINE    
We report an unusual occurrence of spontaneous pigmentary regression with a desmoplastic reaction in a neonatally eroded giant congenital melanocytic nevus. This process has been documented with photographs and skin biopsy specimens. Neonatal histology demonstrated connective tissue proliferation. Histology at age 5 years also demonstrated a very high proportion of amelanotic dermal nevus cells. Regression of pigmentation in our patient may be due to a decrease in melanin production by dermal nevus cells rather than a decrease in their number.
Julia K Gass; John W Grant; Per N Hall; David J Atherton; Nigel P Burrows
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric dermatology     Volume:  23     ISSN:  0736-8046     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    2006 Nov-Dec
Date Detail:
Created Date:  2006-12-12     Completed Date:  2007-10-04     Revised Date:  2009-03-03    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  567-70     Citation Subset:  IM    
Depatment of Dermatology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.
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MeSH Terms
Child, Preschool
Infant, Newborn
Nevus, Pigmented / diagnosis*,  pathology*
Remission, Spontaneous

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