Document Detail


Clinical and research markers of oxidative stress in chronic kidney disease.
MedLine Citation:
PMID:  23339563     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Context: Kidney-related pathologies have increasing prevalence rates, produce a considerable financial burden, and are characterized by elevated levels of oxidative stress (OS). Objective: This review examines relationships between chronic kidney disease (CKD) and markers of OS and antioxidant status (AS). Methods: A systematic review of MEDLINE-indexed clinical trials, randomized controlled trials and comparative studies that examined OS and AS was performed. Results and conclusion: Several markers emerged as well-suited indicators of OS and AS in CKD: malondialdehyde, F2-isoprostanes, lipid hydroperoxides, asymmetric dimethylarginine, 8-oxo-7,8-dihydro-2'-deoxyguanosine, protein carbonyls, advanced oxidation protein products and glutathione-related activity.
Authors:
Patrick Steven Tucker; Vincent James Dalbo; Thin Han; Michael Ian Kingsley
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-23
Journal Detail:
Title:  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals     Volume:  -     ISSN:  1366-5804     ISO Abbreviation:  Biomarkers     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606000     Medline TA:  Biomarkers     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Clinical Biochemistry Laboratory, Institute for Health and Social Science Research, Central Queensland University , Rockhampton, QLD , Australia .
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