Document Detail


Clinical research into Qufeng Zhidong Recipe used to treat 31 children with tic disorder.
MedLine Citation:
PMID:  21053620     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the therapeutic effect and adverse reaction of Qufeng Zhidong Recipe (a recipe for dispelling wind to stop abnormal movement) used to treat children with tic disorder (TD).
METHODS: The enrolled patients were randomized into a TCM group (31 cases) treated with Qufeng Zhidong Recipe and a Western medicine group (30 cases) treated with haloperidol and trihexyphenidyl. Two courses of treatment were observed with 12 weeks as one course. The therapeutic effect and adverse reaction were assessed with Yale Global Tic Severity Scale (YGTSS), Tic Symptom Score Scale (TSSS), TCM Syndrome Score Scale (TCMSSS), Treatment Emergent Symptom Scale (TESS) and laboratory examinations.
RESULTS: The total effective rate was 100% in the TCM group and 60% in the Western medicine group with statistical significance in difference (P < 0.05). All the scores in the TCM group were better than those in the Western medicine group (P < 0.05).
CONCLUSION: Qufeng Zhidong Recipe can obviously relieve the symptoms and signs of TD children without toxic side-effects.
Authors:
Min Wu; Guang-Hua Xiao; Jian-Ming Zhang; Xin Zhang; Bo Ma; Shu-Xia Wang; Ya-Bing Zhou; Jing-Yan Zhang
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine     Volume:  30     ISSN:  0255-2922     ISO Abbreviation:  J Tradit Chin Med     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-11-08     Completed Date:  2010-12-07     Revised Date:  2011-01-25    
Medline Journal Info:
Nlm Unique ID:  8211546     Medline TA:  J Tradit Chin Med     Country:  China    
Other Details:
Languages:  eng     Pagination:  163-70     Citation Subset:  IM    
Affiliation:
Xinhua Hospital affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200092, China. xinhuayiyuan123@126.com
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Drugs, Chinese Herbal / adverse effects,  therapeutic use*
Female
Humans
Male
Tic Disorders / drug therapy*
Chemical
Reg. No./Substance:
0/Drugs, Chinese Herbal; 0/qufeng zhidong

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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