Document Detail

Clinical and radiologic outcome of off-pump coronary surgery at 12 months follow-up: a prospective randomized trial.
MedLine Citation:
PMID:  16731135     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: After more than a decade of experience with off-pump coronary bypass surgery, still no consensus exists concerning its benefit on clinical outcome compared to the on-pump technique. In this 12-month follow-up, we compare off-pump and on-pump surgery on the appearance of graft patency, myocardial function, and clinical outcome. METHODS: One hundred twenty patients were randomized to off-pump or on-pump coronary surgery. Angiography was performed intraoperatively, at 3 and 12 months. Global myocardial function was estimated by magnetic resonance imaging (MRI) preoperatively and 12 months postoperatively, as well as functional class and stress testing. RESULTS: After 12 months internal mammary artery patency was 94% in the off-pump group and 96% in the on-pump group. Vein graft patency was 80% and 87%, respectively. No statistically significant difference between the two groups existed. There were no differences in exercise capacity improvement and attenuation of symptoms between the groups. CONCLUSIONS: At 12-months follow-up, off-pump coronary bypass surgery provided the same angiographic graft patency as the on-pump technique. Improvement in functional class and exercise capacity was the same in both groups.
Per Snorre Lingaas; Per Kristian Hol; Runar Lundblad; Kjell Arne Rein; Lars Mathisen; Hans-Jørgen Smith; Rune Andersen; Erik Thaulow; Tor Inge Tønnesen; Jan Ludvig Svennevig; Sigurd Nitter Hauge; Per Morten Fredriksen; Marit Andersen; Erik Fosse
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  81     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-29     Completed Date:  2007-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  2089-95     Citation Subset:  AIM; IM    
Department of Thoracic and Cardiovascular Surgery, Rikshospitalet University Hospital, Oslo, Norway.
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MeSH Terms
Angina Pectoris / epidemiology
Coronary Angiography*
Coronary Artery Bypass, Off-Pump / statistics & numerical data*
Coronary Restenosis / epidemiology*,  radiography
Exercise Test
Follow-Up Studies
Graft Occlusion, Vascular / epidemiology,  radiography
Internal Mammary-Coronary Artery Anastomosis
Magnetic Resonance Imaging
Middle Aged
Myocardium / pathology
Postoperative Complications / epidemiology
Prospective Studies
Saphenous Vein / transplantation
Single-Blind Method
Treatment Outcome
Comment In:
Ann Thorac Surg. 2006 Jun;81(6):2095-6   [PMID:  16731136 ]
Ann Thorac Surg. 2007 Feb;83(2):724   [PMID:  17258031 ]

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