Document Detail


Clinical and prognostic significance of vasculitis as an early manifestation of connective tissue disease syndromes.
MedLine Citation:
PMID:  6149715     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The courses of 18 patients with arthritis and vasculitis in the first 2 years after onset of disease (mean follow-up, 54 months) were studied. The patients were categorized as having rheumatoid vasculitis, systemic vasculitis, and undifferentiated connective tissue syndrome. These patients cannot be distinguished on basis of organ involvement by vasculitis or histopathologic findings on biopsy, but can be separated clinically by the extent of joint involvement and the presence or absence of rheumatoid factor and antinuclear antibody. Early onset of vasculitis is associated with a poor outcome, especially in patients with rheumatoid arthritis, with rapid progression to vasculitic involvement of the viscera, resulting in death. On the basis of the 54-month follow-up period involving this selected series, the prognosis of patients with systemic vasculitis and undifferentiated connective tissue syndrome appears more favorable than that of patients with rheumatoid vasculitis.
Authors:
S Lakhanpal; D L Conn; J T Lie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of internal medicine     Volume:  101     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1984-12-18     Completed Date:  1984-12-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  743-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Arthritis, Rheumatoid / complications
Connective Tissue Diseases / complications*,  mortality
Female
Follow-Up Studies
Humans
Male
Middle Aged
Polyarteritis Nodosa / complications
Prognosis
Time Factors
Vasculitis / etiology*,  mortality

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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