| Clinical and prognostic categorization of extraintestinal nontyphoidal Salmonella infections in infants and children. | |
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MedLine Citation:
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PMID: 10524956 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The study included 172 patients, aged 0-15 years, for whom at least 1 nonfecal, nonurinary specimen was culture-positive for nontyphoidal Salmonella. Ninety-five percent had positive blood cultures. Immunocompromising diseases were found in 19% of 74 infants and 77% of 98 children. Associations between the study factors and outcomes, as localized infection or death, were assessed by logistic regression analysis. Thirty-three patients had localized infections. An adjusted risk factor for development of localized infections was an age of <12 months (P=.003). There were 17 deaths. The case-fatality rates were 43% and 10% for immunocompromised and 5% and 0% for nonimmunocompromised infants and children, respectively. Adjusted risk factors for death were age of <12 months (P=.006), inappropriate antimicrobial therapy (P=.014), meningitis or culture-proven pneumonia due to nontyphoidal Salmonella (P=.004), and immunocompromised status (P<.001). The clinical courses and prognoses for infants and children with extraintestinal infection due to nontyphoidal Salmonella can be categorized into 4 groups according to the characteristics of age (infants vs. children) and host status (immunocompromised vs. nonimmunocompromised). |
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Authors:
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S Sirinavin; P Jayanetra; A Thakkinstian |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 29 ISSN: 1058-4838 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 1999 Nov |
Date Detail:
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Created Date: 1999-12-02 Completed Date: 1999-12-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1151-6 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Ramathibodi Hospital, Bangkok 10400, Thailand. rassr@mahidol.ac.th |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Child Child, Preschool Diarrhea / etiology Female Humans Infant Infant, Newborn Leukocyte Count Male Multivariate Analysis Prognosis Risk Factors Salmonella Infections / immunology, mortality* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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