| Clinical profile and treatment outcome of tubercular pleurisy in pediatric age group using DOTS strategy. | |
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MedLine Citation:
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PMID: 20469730 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A significant proportion of global tuberculosis (TB) caseload is contributed by children. Management of pediatric TB especially EPTB is challenging. The present study was designed to study demographic, clinical profile and treatment outcome of DOTS strategy for pediatric tubercular pleurisy. AIM: To study the efficacy of DOTS strategy. METHODS: Retrospective analysis of 106 TB pleurisy children treated with DOTS. RESULTS: Mean age was 10.8 years (median age 12.2 years) with more females (51.9%) than males (48.1%) chi1(2) = 0.15; P = 0.698 (NS). In the age group of 0-5, 6-10 and 11-14 years, there were 15.1%, 30.2% and 54.7% patients respectively. Fever was the commonest symptom (98.1%) followed by cough (77.4%) and chest pain (55.7%). History of contact could be elicited only in 2/3rd of cases unilateral effusion (61.3%) was commonest, followed by empyema (22.6%), massive effusion and broncho-pleural fistula each in 13.2% cases respectively. Bilateral effusion was seen in 3.8% cases only. Conventional methods (mantoux, radiograph, ultrasound, pleural aspiration) and minimal invasive surgical techniques, percutaneous pleural biopsy were done to arrive at the diagnosis. Diagnosis was made by X-ray Chest in 92.5%, exudative pleural fluid (100%) predominantly lymphocytic in 85.8%, positive AFB smear and culture in 4.7 and 5.7% cases respectively. Category I, II and III was started on 35.9%, 2.8% and 61.3% patients respectively. Overall treatment completion rate was 94.3%, 4.7% default rate, 0.9% failure rate and no deaths. CONCLUSION: The study confirms early detection by simple tests and ensuring complete treatment using DOTS strategy. |
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Authors:
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Sangeeta Sharma; Rohit Sarin; U K Khalid; N Singla; P P Sharma; D Behera |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Indian journal of tuberculosis Volume: 56 ISSN: 0019-5707 ISO Abbreviation: Indian J Tuberc Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2010-05-17 Completed Date: 2010-06-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0373027 Medline TA: Indian J Tuberc Country: India |
Other Details:
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Languages: eng Pagination: 191-200 Citation Subset: IM |
Affiliation:
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LRS Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi - 110 030. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Antitubercular Agents / therapeutic use Bronchial Fistula / microbiology Chest Pain / etiology Child Child, Preschool Cough / etiology Directly Observed Therapy* Empyema / microbiology Female Fever / etiology Humans India Infant Infant, Newborn Male Pleural Cavity / microbiology Pleural Effusion / microbiology Radiography, Thoracic Retrospective Studies Sputum / microbiology Treatment Outcome Tuberculosis, Pleural / diagnosis*, drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Antitubercular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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