Document Detail


Clinical profile and outcome of abdominal tuberculosis in Indian children.
MedLine Citation:
PMID:  17909673     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Diagnosis of tuberculosis among children poses technical and operational challenges, more so in abdominal tuberculosis (ATB), where the protean clinical manifestations continue to challenge the physicians in its diagnosis and therapy. METHODS: Medical records of 115 patients who were diagnosed with ATB over a period of six years were studied retrospectively. Details of history, physical examination and investigations, treatment and outcome of therapy were evaluated. RESULTS: The mean age of the patients was 6.4 years. Commonest symptom at presentation was abdominal pain, followed by fever. Nine patients presented with acute abdomen. Mantoux test was positive in 33 percent and accelerated BCG reaction was found in 36.5 percent. Evidence of primary focus was found in 40 percent of chest radiographs. Commonest ultrasonography and computed tomography findings were mesenteric thickening, followed by intra-abdominal lymphadenopathy. Tuberculous infection could be confirmed in 38 patients. The classical plastic variety was the commonest type of ATB found. A complete cure with antituberculous drugs was documented in over 90 percent of the patients. CONCLUSION: In high prevalence zones, ATB should be considered as a differential diagnosis in children presenting with non-specific constitutional symptoms and abdominal pain. When confirmatory tests are negative or not available, supportive investigations and clinical suspicion should be considered strongly for diagnosis of ATB to avoid delay in treatment. Response to therapy in such conditions indirectly confirms diagnosis. Timely use of laparoscopy and laparotomy may be required for confirmation of diagnosis.
Authors:
S Basu; S Ganguly; P K Chandra; S Basu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  48     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-10-02     Completed Date:  2007-11-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  900-5     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, North Bengal Medical College and Hospital, Sushrutnagar, Darjeeling, India. drsriparnabasu@rediffmail.com
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MeSH Terms
Descriptor/Qualifier:
Antitubercular Agents / therapeutic use
Child
Child, Preschool
Female
Hospitals, University
Humans
India / epidemiology
Infant
Male
Retrospective Studies
Treatment Outcome
Tuberculosis, Gastrointestinal / diagnosis,  drug therapy,  epidemiology*,  physiopathology
Chemical
Reg. No./Substance:
0/Antitubercular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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