Document Detail


Clinical profile in gelatinous bone marrow transformation.
MedLine Citation:
PMID:  15266925     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study the clinical spectrum associated with gelatinous bone marrow transformation (GMT). METHODS: All subjects whose bone marrow aspiration showed pink purple material on Leishman stain underwent a detail history, clinical examination and investigation (biochemical/microbiological/radiological). Additionally, in each subject the smear was stained with special stains of Periodic Acid Schiff and Alcian blue. RESULTS: Out of total 1498 marrows, 65 showed evidence of GMT. All of these had anaemia. The associated clinical spectra of diseases noticed were: Infection (31 cases), Nutritional deficiency (5 cases), Haematological disorders (Aplastic/toxic depression) (17 cases), Malignancies (3 cases), and Miscellaneous (9 cases). CONCLUSION: Based on the heterogenecity of associated clinical disorders, GMT indicates severe illness and not a particular disease. GMT may be a result of bioregulatory process (which presently needs further prospective studies) that are activated in different pathologic conditions but resulting in similar lesion in the bone marrow and so till then it may be concluded that GMT is a symptom of bone marrow.
Authors:
R Sen; S Singh; H Singh; A Gupta; J Sen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  51     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2004-07-22     Completed Date:  2004-08-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  585-8     Citation Subset:  IM    
Affiliation:
Department of Pathology, Pt. BD Sharma PGIMS, Rohtak (Haryana), India.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Biopsy, Needle
Bone Marrow / pathology*
Bone Marrow Diseases / complications,  pathology*
Child
Child, Preschool
Female
Humans
Infant
Male
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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