| Clinical profile of Streptococcus agalactiae native valve endocarditis. | |
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MedLine Citation:
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PMID: 14661005 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Streptococcus agalactiae is an unusual pathogen in adults who are not pregnant. S agalactiae endocarditis is a poorly defined entity because it is uncommon; in contrast to other streptococcal endocarditis, it bears a high mortality rate. The aim of this study was to define its clinical, prognostic, and therapeutic profile on the basis of a series of 9 consecutive patients. METHODS: We conducted a prospective and multicenter study of patients with infectious endocarditis in which 310 episodes were included. RESULTS: S agalactiae grew in 9 patients (3%) who had no valve prosthesis. All patients except 1 had underlying diseases, and all patients had serious complications; the most common complications were major emboli, heart failure, and shock. The valve affected was the mitral valve in 4 patients, the aortic valve in 2 patients, both the mitral and aortic valves in 2 patients, and the tricuspid valve in 1 patient. All episodes were on native valves. Vegetations tended to be large (maximal diameter >10 mm in all patients), very mobile, and pedunculated. An abscess was found in 2 patients, and a perforation of the valve developed in 3 patients. Five patients died (mortality rate, 56%), 3 of whom had received antibiotic therapy alone. The 4 patients who survived underwent combined medical-surgical therapy. CONCLUSION: S agalactiae native valve endocarditis is very aggressive, and early surgery should be considered to prevent the destruction of valves and development of serious complications. |
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Authors:
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María Jesús Rollán; José Alberto San Román; Isidre Vilacosta; Cristina Sarriá; Javier López; María Acuña; José Luis Bratos |
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Publication Detail:
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Type: Journal Article; Multicenter Study |
Journal Detail:
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Title: American heart journal Volume: 146 ISSN: 1097-6744 ISO Abbreviation: Am. Heart J. Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2003-12-08 Completed Date: 2004-01-13 Revised Date: 2006-02-27 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: United States |
Other Details:
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Languages: eng Pagination: 1095-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, Hospital Universitario del Río Hortega, Valladolid, Spain. asanroman@secardiologia.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Aortic Valve / microbiology, ultrasonography Endocarditis, Bacterial / complications, microbiology*, ultrasonography Female Humans Male Middle Aged Mitral Valve / microbiology, ultrasonography Prospective Studies Streptococcal Infections / microbiology*, ultrasonography Streptococcus agalactiae* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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