Document Detail


Clinical predictors of epidemic outcome in meningococcal infection in Jos, Nigeria.
MedLine Citation:
PMID:  9491173     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The clinical predictors of outcome in children admitted into the Emergency Paediatric Unit at the Jos University Teaching Hospital with meningococcal infection during an out-break of the disease (between February-April 1996) were studied. Eighty seven children were admitted with meningococcal infection during the period. There were 60 males and 27 females (M:F = 2.2:1), aged between five weeks and 16 years (mean 7.7 +/- 4.9 years). Overall mortality was 26.4 per cent. Eighty five per cent of the patients who presented in shock died, compared with nine per cent who presented without shock (p < 0.000001). Similarly, 65% of the patients who presented in coma died, compared with 12.5% who did not present in coma (p < 0.000001). Other factors associated with a poor outcome included age one year and below, petechial/purpuric rash on presentation and meningococcaemia. Complications were documented in 27 (31.0%) of the patients, consisting mainly of deafness, extensive vasculitis/ulceration of extremities, gangrene of legs hemiparesis and cranial nerve palsies.
Authors:
I A Angyo; E S Okpeh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  East African medical journal     Volume:  74     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1998-03-23     Completed Date:  1998-03-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  KENYA    
Other Details:
Languages:  eng     Pagination:  423-6     Citation Subset:  IM    
Affiliation:
Infectious Disease Unit, Jos University Teaching Hospital, Nigeria.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Age Distribution
Child
Child, Preschool
Disease Outbreaks*
Female
Hospital Mortality
Hospitals, University
Humans
Infant
Male
Meningococcal Infections / complications*,  mortality*
Nigeria
Outcome Assessment (Health Care)
Predictive Value of Tests
Prognosis
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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