Document Detail

Clinical prediction of response to lithium prophylaxis in bipolar patients: the importance of the previous pattern of course of the illness.
MedLine Citation:
PMID:  2116228     Owner:  NLM     Status:  MEDLINE    
The response to lithium prophylaxis was evaluated in a sample of bipolar patients subdivided into groups, according to the previous pattern of course for their illness: MDI (sequence mania-depression-free interval), DMI (sequence depression-mania-free interval), CC-LC (continuous circular course with long cycles), CC-RC (continuous circular course with rapid cycles), IRR (irregular course). The percentage of responders to treatment was significantly different among the five groups, and the difference could be ascribed mainly to the high response rate in the MDI group and the low response rate in the DMI and CC-RC groups. These data suggest that the classification of bipolar patients on the basis of the previous pattern of their course of illness may be useful for predicting lithium response.
M Maj
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical neuropharmacology     Volume:  13 Suppl 1     ISSN:  0362-5664     ISO Abbreviation:  Clin Neuropharmacol     Publication Date:  1990  
Date Detail:
Created Date:  1990-09-07     Completed Date:  1990-09-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607910     Medline TA:  Clin Neuropharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S66-70     Citation Subset:  IM    
Institute of Medical Psychology and Psychiatry, First Medical School, University of Naples, Italy.
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MeSH Terms
Bipolar Disorder / classification,  prevention & control*,  psychology
Lithium / administration & dosage,  therapeutic use*
Lithium Carbonate
Middle Aged
Reg. No./Substance:
554-13-2/Lithium Carbonate; 7439-93-2/Lithium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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