Document Detail

Clinical prediction of the adult respiratory distress syndrome.
MedLine Citation:
PMID:  3000686     Owner:  NLM     Status:  MEDLINE    
The use of clinical, physiologic, and laboratory parameters in the prediction or early detection of ARDS has been reviewed. From both a clinical and research standpoint, the ability to identify patients at risk is extremely important. The selection of patients according to predisposing clinical events has been the most successful thus far. The use of physiologic variables and gauges of injury severity have been of limited value, particularly for assessing ARDS risk in the individual patient. Only a handful of the proposed mediators or markers of acute lung injury have been studied prospectively in patients at risk. Of these, factor VIII antigen, lactoferrin, and phospholipase A2 appear the most promising as laboratory tests for selecting patients at risk. In the future it may be possible by using sophisticated statistical analysis techniques to combine important clinical, physiologic, and laboratory information into a numerical ARDS risk index, essentially assigning a probability of ARDS in individual patients.
R J Maunder
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in chest medicine     Volume:  6     ISSN:  0272-5231     ISO Abbreviation:  Clin. Chest Med.     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1986-02-18     Completed Date:  1986-02-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907612     Medline TA:  Clin Chest Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  413-26     Citation Subset:  IM    
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MeSH Terms
Blood Platelets / physiology
Complement Activation
Endothelium / physiology
Fibronectins / physiology
Heart / physiopathology
Leukopenia / etiology
Lung / physiopathology
Neutrophils / physiology
Peptidyl-Dipeptidase A / blood
Respiratory Distress Syndrome, Adult / diagnosis,  etiology*,  physiopathology
Reg. No./Substance:
0/Fibronectins; EC A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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