Document Detail


Clinical performance of etodolac in patients with osteoarthritis and rheumatoid arthritis.
MedLine Citation:
PMID:  7744125     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effectiveness of etodolac in the treatment of patients with osteoarthritis (OA) and with rheumatoid arthritis (RA) has been well documented in controlled clinical trials. The superiority of etodolac, 300 mg twice daily, over placebo has already been established in short-term trials involving patients with OA. During long-term treatment, significant (p < 0.05) improvement was observed in patients with OA and RA as measured by a variety of efficacy parameters. In comparative studies for OA, etodolac was more effective than conventional indomethacin; naproxen, sustained-release diclofenac, and piroxicam were comparably effective. The newer sustained-release formulation of etodolac is as effective as the conventional etodolac formulation when used to treat patients with OA and those with RA.
Authors:
E M Veys
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of rheumatology and inflammation     Volume:  14     ISSN:  0140-1610     ISO Abbreviation:  Eur J Rheumatol Inflamm     Publication Date:  1994  
Date Detail:
Created Date:  1995-06-15     Completed Date:  1995-06-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7805765     Medline TA:  Eur J Rheumatol Inflamm     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  23-7     Citation Subset:  IM    
Affiliation:
Department of Rheumatology, University Hospital of Gent, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Arthritis, Rheumatoid / drug therapy*
Clinical Trials as Topic
Etodolac / therapeutic use*
Humans
Middle Aged
Osteoarthritis / drug therapy*
Time Factors
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 41340-25-4/Etodolac

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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