Document Detail

Clinical and pathophysiological aspects of neurological complications in renal failure.
MedLine Citation:
PMID:  1332359     Owner:  NLM     Status:  MEDLINE    
A review of the neurological complications presenting in uremia and an account of their presumed pathophysiology is given. With the introduction of different dialytic procedures during the last twenty years, the incidence and severity of neurological complications have declined. Nevertheless, some disturbances related to the uremic syndrome fail to respond to dialytic therapy and these therapeutic measures may even be responsible for the appearance of some new abnormalities. The clinical manifestations of uremic encephalopathy and polyneuropathy are presented. The review of the presumed pathophysiology of these syndromes illustrates the still existing controversies. Nevertheless, some promising new lines of research are reviewed. In addition, some complications of uremic treatment, including dialysis disequilibrium syndrome and dialysis encephalopathy are presented.
P P De Deyn; V K Saxena; H Abts; F Borggreve; R D'Hooge; B Marescau; R Crols
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta neurologica Belgica     Volume:  92     ISSN:  0300-9009     ISO Abbreviation:  Acta Neurol Belg     Publication Date:  1992  
Date Detail:
Created Date:  1992-12-10     Completed Date:  1992-12-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0247035     Medline TA:  Acta Neurol Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  191-206     Citation Subset:  IM    
Department of Medicine, University of Antwerp, U.I.A., Wilrijk.
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MeSH Terms
Brain Diseases, Metabolic / etiology*,  physiopathology
Kidney Failure, Chronic / complications*
Peripheral Nervous System Diseases / etiology,  physiopathology
Renal Dialysis / adverse effects
Seizures / physiopathology
Uremia / physiopathology,  therapy

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