Document Detail


Clinical pathology and retinal vascular structure in the Bardet-Biedl syndrome.
MedLine Citation:
PMID:  7880798     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A comparative study of clinical pathology and retinal vascular structure is described as studied by vascular casting in an eye of a patient with the Bardet-Biedl syndrome. At the time of examination the eye had been almost blind for at least 4 years. The histopathological examination showed a largely uniform loss of the outer retinal layers. The gross pathological examination of the cast ocular fundus showed three distinct zones, an inner zone inside the temporal vascular arcades where retinal vessels had been cast, a mid peripheral zone with bone spicules, and a peripheral zone with neither cast vessels nor bone spicules. The findings are discussed in relation to possible pathophysiological mechanisms involved in the development of retinal dystrophy in the Bardet-Biedl syndrome.
Authors:
T Bek; T Rosenberg
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  79     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-04-10     Completed Date:  1995-04-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  76-80     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Arhus University Hospital, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Laurence-Moon Syndrome / pathology*
Middle Aged
Retinal Degeneration / pathology
Retinal Vessels / pathology*
Comments/Corrections

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