| Clinical pathology of the cardiac conduction system. | |
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MedLine Citation:
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PMID: 12956332 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Abnormal architecture of the conduction system affects both the normally structured and the congenitally malformed heart. While the majority of malformed hearts have more-or-less normal arrangements of the conduction system, there are others with significant deviations. In particular, the derangements are related to malalignment of the ventricular septum in the case of the atrioventricular conduction tissues, and to atrial arrangement with regard to the sinus node. Congenital heart block can occur in isolation or in association with congenital heart defects. The anatomical substrate in heart block is an interruption of the atrioventricular conduction system. Lesions of the conduction system are also found in cases of sudden cardiac death in adults. Whether such lesions are congenital or 'acquired' as part of the ageing process remains to be clarified. |
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Authors:
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Siew Yen Ho |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Novartis Foundation symposium Volume: 250 ISSN: 1528-2511 ISO Abbreviation: Novartis Found. Symp. Publication Date: 2003 |
Date Detail:
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Created Date: 2003-09-05 Completed Date: 2004-04-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9807767 Medline TA: Novartis Found Symp Country: England |
Other Details:
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Languages: eng Pagination: 210-21; discussion 221-6, 276-9 Citation Subset: IM |
Affiliation:
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Paediatrics, National Heart & Lung Institute, Faculty of Medicine, Imperial College, Royal Brompton and Harefield NHS Trust, London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Death, Sudden Fetus / anatomy & histology, pathology, physiology Heart Block Heart Conduction System / embryology, pathology*, physiology Heart Defects, Congenital / pathology* Heart Diseases / congenital, pathology Humans |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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