Document Detail


Clinical, pathological, and antibody pattern of latent celiac disease: report of three adult cases.
MedLine Citation:
PMID:  8855749     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the clinical, pathological, and serological findings of three adult patients with latent celiac disease. The initial intestinal biopsies, which were normal, were carried out in the first case during an upper gastrointestinal endoscopy performed for a duodenal ulcer, in the second case for first-degree familiarity with a celiac patient, and in the third case because of the presence of malabsorption symptoms. In all three cases, intraepithelial lymphocytes were within the normal range in the first biopsy and cannot, therefore, be considered as a marker of latent celiac disease. In only two of the three patients was it possible to carry out the search for the serum antibodies connected with celiac disease at the time of the first biopsy. In both these cases, the antijejunal antibodies were present before the development of the intestinal lesions.
Authors:
G R Corazza; M L Andreani; F Biagi; F Bonvicini; M Bernardi; G Gasbarrini
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  91     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1996-11-13     Completed Date:  1996-11-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2203-7     Citation Subset:  IM    
Affiliation:
Dipartimento di Medicina Interna dell'Università dell'Aquila, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antibodies / analysis
Biopsy
Celiac Disease / diagnosis*
Duodenum / pathology
Enzyme-Linked Immunosorbent Assay / methods
Female
Fluorescent Antibody Technique, Indirect
Gliadin / immunology
Humans
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Intestinal Mucosa / pathology
Jejunum / immunology
Lymphocytes / pathology
Male
Middle Aged
Myofibrils / immunology
Chemical
Reg. No./Substance:
0/Antibodies; 0/Immunoglobulin A; 0/Immunoglobulin G; 9007-90-3/Gliadin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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