Document Detail

Clinical and pathologic correlates of stillbirths in a single institution.
MedLine Citation:
PMID:  9740519     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To evaluate risk factors, placental and pathologic determinants of stillbirths. METHODS: A retrospective analysis of stillbirths > or = 25 weeks was performed. Clinical data was compared to a randomized control group. Statistical analysis included chi square test, student t test, and logistic regression. RESULTS: One hundred and fifteen stillbirths and 193 controls were analyzed. Maternal age, nulliparity, tobacco use, previous induced abortions, anticardiolipid antibodies, elevated maternal serum alpha feto protein, twins, and amniocentesis, were significantly associated with stillbirth. Logistic regression analysis showed only maternal age, tobacco use, small for gestational age (SGA), previous induced abortions, decreasing gestational age as independent significant variables. The stillbirth baby was 6.8 times more likely to be SGA and 11.9 times more likely to be preterm. Primary pathologic diagnoses were placental factors (37%), cord complications (28%), and fetal causes (15%), 17% had maternal risk factors only and 3% had no known risk factors. Diagnosis was suggested by pathology in 40% of cases. CONCLUSIONS: Stillbirth delivery is associated with older, nulliparous patients with prenatal complications resulting in intrauterine growth retardation and prematurity. Perinatal histopathologic examination is important in diagnosis. Utilizing an extensive testing protocol will reduce the diagnosis of unexplained stillbirth.
D Ogunyemi; U Jackson; S Buyske; A Risk
Related Documents :
7755069 - A randomized, prospective study of adjunctive ceftizoxime in preterm labor.
18756429 - Dilation and evacuation of a single fetus after midtrimester prom in previable twin pre...
9288339 - Effects of timing of conception on birth weight and preterm delivery of natural family ...
7847109 - Cervical inflammation and preterm delivery in pregnant women with a history of preterm ...
19900049 - Perinatal outcomes and complications of pregnancy in women with immune thrombocytopenic...
10508879 - Fetal membrane histology in preterm premature rupture of membranes: comparison to contr...
24750419 - The effectiveness of weight management interventions in breastfeeding women-a systemati...
17091409 - Prevention of postpartum hemorrhage by uterotonic agents: comparison of oxytocin and me...
3544659 - Fundal height growth in rural africa.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  77     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-09-24     Completed Date:  1998-09-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  722-8     Citation Subset:  IM    
Morristown Memorial Hospital, New Jersey 07962, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Case-Control Studies
Fetal Death / etiology*,  pathology*
Gestational Age
Logistic Models
Odds Ratio
Pregnancy Complications
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Red cell age and susceptibility to malaria during pregnancy.
Next Document:  Interest in alternative birth settings in Finland.