| Clinical and parasitological aspects of itching caused by onchocerciasis in Morogoro, Tanzania. | |
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MedLine Citation:
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PMID: 11214098 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A clinical and parasitological assessment of onchodermatitis was conducted in a rural area of Morogoro district, Tanzania. The study population consisted of 1,005 individuals aged > or = 5 years: 749 from a hyper-endemic community and 256 from a hypo-endemic. The prevalence of troublesome itching was 67.0% in the hyper-endemic community but only 5% (13/256) in the hypo-endemic. The corresponding prevalences of nodules among the adult male subjects were 77.7% (171/220) and 2.3% (2/86). The most common onchocercal skin lesion in the hyper-endemic community was chronic papular onchodermatitis (CPOD) manifested by itching, which was often very severe. There was a strong association between skin itching and endemicity (r = 0.75; P < 0.001). The prevalence of CPOD in the hyper-endemic community was significantly higher in males than females (P< 0.001). CPOD was only observed in subjects aged > or = 7 years. Many of the subjects were checked for microfilaridermia, by skin-snipping. The prevalence of microfilaridermia [58.2% (393/675) v. 6.2% (3/48)] and its geometric mean intensity (8.9 v. 1.0 microfilariae/mg skin snip) were both higher in the hyper-endemic community than the hypo-endemic. Itching appears to be related to reactive onchodermatitis. |
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Authors:
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W H Makunde; F M Salum; J J Massaga; M S Alilio |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of tropical medicine and parasitology Volume: 94 ISSN: 0003-4983 ISO Abbreviation: Ann Trop Med Parasitol Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2001-02-13 Completed Date: 2001-03-01 Revised Date: 2009-05-18 |
Medline Journal Info:
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Nlm Unique ID: 2985178R Medline TA: Ann Trop Med Parasitol Country: England |
Other Details:
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Languages: eng Pagination: 793-9 Citation Subset: IM |
Affiliation:
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National Institute for Medical Research, Tanga, Tanzania. nimr.amani@tanga.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Aged Child Comorbidity Endemic Diseases* Female Humans Male Middle Aged Onchocerciasis / epidemiology* Prevalence Pruritus / epidemiology*, parasitology Sex Factors Skin / parasitology Tanzania / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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