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Clinical outcomes of surgery of mitral valve regurgitation and coronary artery bypass grafting.
MedLine Citation:
PMID:  17670600     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The impact of etiology of associated mitral valve regurgitation and a valve procedure on operative and long-term outcomes after coronary bypass grafting surgery is yet to be clearly defined. Results of combined coronary artery bypass grafting and valve procedures for mitral valve regurgitation were retrospectively analyzed in 468 patients. The regurgitation was of ischemic in 45%, degenerative in 55% and 78% valve repairs, 22% valve replacements were performed. Severe coronary artery disease, acute myocardial infarction, low ejection fraction, ischemic mitral regurgitation, advanced heart failure symptoms, failure to use internal mammary artery, valve replacement surgery, and emergency operations are predictors of operative mortality. The 5-year survivals for propensity-matched patients of ischemic and degenerative disease were similar (66%), but 67% vs. 83%, respectively, for unmatched patients. Low ejection fraction (<35%), advanced age (>67 years), valve replacement surgery, residual mitral regurgitation, and severe coronary artery disease were predictors of poor long-term survival. Left ventricular remodeling processes, optimal valve procedure without residual mitral regurgitation and left ventricular function are important determinants of long-term outcome than the etiology of valve regurgitation.
Authors:
Srikrishna Sirivella; Isaac Gielchinsky
Publication Detail:
Type:  Journal Article     Date:  2006-05-03
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  5     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2007-08-02     Completed Date:  2007-08-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  392-7     Citation Subset:  -    
Affiliation:
Newark Beth Israel Medical Center, Department of Cardiovascular and Thoracic Surgery, Newark University of Medicine & Dentistry of New Jersey, Newark, NJ 07112, USA. ssirivella475@yahoo.com
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