Document Detail

Clinical outcomes of elective single morula embryo transfer versus elective single blastocyst embryo transfer in IVF-ET.
MedLine Citation:
PMID:  22382643     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare the clinical outcomes of elective single morula embryo transfer (eSMET) versus elective single blastocyst embryo transfer (eSBET) in selected patients.
METHODS: This study was a retrospective study which analyzed for 271 cycles in women under 37 years of age who are undergoing their first or second trial of in vitro fertilization-embryo transfer (IVF-ET) from January 2008 to December 2009. The eSMET was performed on day 4 (n = 130) and the eSBET was conducted on day 5 (n = 141).
RESULTS: The clinical pregnancy rate (51.5% vs. 51.8%, p = 0.97), implantation rate (52.3% vs. 52.5%, p = 0.98), and live birth rate (39.2% vs. 44.7%, p = 0.36) were similar in the eSMET and eSBET groups, respectively. The miscarriage rate of the eSMET group (23.9%) was slightly higher than that of the eSBET group (13.7%) (p = 0.12), without reaching statistical significance. There was only one case of monozygotic twin pregnancy in each group.
CONCLUSIONS: The clinical outcomes of day 4 eSMET were comparable to those of day 5 eSBET. Therefore, day 4 eSMET is a viable option or an alternative to day 5 eSBET, with no difference in success rates.
Sang Min Kang; Sang Won Lee; Hak Jun Jeong; San Hyun Yoon; Min Whan Koh; Jin Ho Lim; Seong Goo Lee
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Publication Detail:
Type:  Journal Article     Date:  2012-03-01
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  29     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-09     Completed Date:  2012-11-08     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  423-8     Citation Subset:  IM    
Maria Fertility Clinic, Samsung Fire Bldg. 2-1 Beomeo-Dong 3, Suseong-Gu, Daegu, 706-743, Republic of Korea.
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MeSH Terms
Abortion, Spontaneous
Birth Rate
Embryo Implantation
Fertilization in Vitro / methods*
Live Birth*
Ovulation Induction / methods
Pregnancy Rate*
Retrospective Studies
Single Embryo Transfer / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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