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Clinical outcome of nutrition-oriented intervention for primary intestinal lymphangiectasia.
MedLine Citation:
PMID:  21191781     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: primary intestinal lymphangiectasia (PIL) is a rare digestive disease and few studies have focused on the therapeutic effect in PIL patients. This study was undertaken to evaluate nutrition-oriented intervention in children with PIL.
METHODS: four children with PIL were studied. Their medical records were reviewed. Anthropometric measurements and blood tests were performed during a 8-18 month follow-up.
RESULTS: during hospitalization, the 4 patients were subjected to diet intervention. Parenteral nutrition (PN) support was also given to 3 of them. Clinical symptoms and laboratory parameters of the patients were significantly improved at discharge. After discharge, the patients continued diet control, 2 of whom received intermittent PN support. The mean follow-up duration of the 4 patients was 13 months (range, 8-18 months) and they all kept in a stable condition without symptoms relapse. Weight, height and body mass index for age were normal during the follow-up, while total protein, albumin and immunoglobulin concentrations were still slightly below normal level.
CONCLUSIONS: nutrition therapy is effective as a valid and safe therapeutic management for PIL patients. No growth retardation was observed in the 4 children after the therapy, but they are still at risk of nutrient malabsorption. Therefore, they need long-term, regular monitoring and intensive nutritional care.
Authors:
Qing-Ya Tang; Jie Wen; Jiang Wu; Ying Wang; Wei Cai
Publication Detail:
Type:  Journal Article     Date:  2010-12-30
Journal Detail:
Title:  World journal of pediatrics : WJP     Volume:  7     ISSN:  1867-0687     ISO Abbreviation:  World J Pediatr     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2010-12-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101278599     Medline TA:  World J Pediatr     Country:  China    
Other Details:
Languages:  eng     Pagination:  79-82     Citation Subset:  IM    
Affiliation:
Clinical Nutrition Center, Shanghai Jiao Tong University, School of Medicine, Xin Hua Hospital, Shanghai, China.
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