Document Detail


Clinical outcome and microvascular blood flow in VAC® and Sorbalgon® treated peri-vascular infected wounds in the groin after vascular surgery - an early interim analysis.
MedLine Citation:
PMID:  22672773     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Vacuum-assisted wound closure (VAC®) therapy is considered to be superior to conventional dressings in the treatment of peri-vascular groin infections after vascular surgery at our department. Therefore, we wanted to perform an early interim analysis of clinical outcome in these seriously ill patients at risk for amputation and death. Patients were randomised to either VAC® (n = 5) or Sorbalgon® (n = 5; best other treatment) therapy after surgical debridement. Non-invasive laser Doppler perfusion imaging (LDPI) studies of the skin adjacent to the undressed wound were performed after 14 days of wound treatment. There were no difference in LDPI values in VAC® versus Sorbalgon® treated patients (P = 0·46). One patient in the VAC® group suffered from two re-bleeding episodes, leading to vascular resection and transfemoral amputation and in the Sorbalgon® group two had a complete wound healing time of more than 4 months and one had a visible interposition bypass graft in the groin after 1 month of treatment. No patient died due to the groin infection. Although not statistically proven, fewer wound treatment failures were recorded in the VAC® group, justifying this early interim analysis. LDPI studies were feasible.
Authors:
Stefan Acosta; Christina Monsen; Magnus Dencker
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-4
Journal Detail:
Title:  International wound journal     Volume:  -     ISSN:  1742-481X     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230907     Medline TA:  Int Wound J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. International Wound Journal © 2012 Blackwell Publishing Ltd and Medicalhelplines.com Inc.
Affiliation:
S Acosta, MD, PhD, Vascular Center Malmö-Lund, Malmö University Hospital, SE-205 02 Malmö, Sweden C Monsen, RN, Vascular Center Malmö-Lund, Malmö University Hospital, SE-205 02 Malmö, Sweden M Dencker, MD, PhD, Department of Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Malmö, Sweden.
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