Document Detail


Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations.
MedLine Citation:
PMID:  10534274     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lipoteichoic and teichoic acids are components of the cell wall of Streptococcus pneumoniae. A recently developed enzyme immunoassay was used in patients with pneumococcal meningitis to investigate lipoteichoic and teichoic acid concentrations in CSF at the first lumbar puncture in relation to the clinical outcome determined by the Glasgow Outcome Scale. Lipoteichoic and teichoic acid concentrations in CSF were significantly associated with neurologic sequelae and mortality in S. pneumoniae meningitis.
Authors:
O Schneider; U Michel; G Zysk; O Dubuis; R Nau
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neurology     Volume:  53     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-11-03     Completed Date:  1999-11-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1584-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurology, University of Göttingen, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Child, Preschool
Disability Evaluation
Female
Glasgow Coma Scale
Humans
Immunoenzyme Techniques / methods
Infant
Infant, Newborn
Lipopolysaccharides / cerebrospinal fluid*
Male
Meningitis, Pneumococcal / cerebrospinal fluid*,  complications,  mortality,  physiopathology*
Middle Aged
Nervous System Diseases / etiology
Osmolar Concentration
Spinal Puncture
Teichoic Acids / cerebrospinal fluid*
Chemical
Reg. No./Substance:
0/Lipopolysaccharides; 0/Teichoic Acids; 56411-57-5/lipoteichoic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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