Document Detail

Clinical outcome in neonates with twin anemia-polycythemia sequence.
MedLine Citation:
PMID:  20417489     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to evaluate neonatal outcome of monochorionic twin pregnancies complicated by twin anemia-polycythemia sequence (TAPS). STUDY DESIGN: A cohort of consecutive monochorionic twins with TAPS with double survivors was included in the study. Each twin pair with TAPS was compared with 2 monochorionic twin pairs who were unaffected by TAPS or twin-to-twin transfusion syndrome and who were matched for gestational age at birth. Neonatal death, severe morbidity, and cerebral injury were studied. RESULTS: We included 19 twin pairs in the TAPS group and 38 control twin pairs. The incidence of neonatal death and severe neonatal morbidity was similar in the TAPS group and control group (3% [1/38] vs 1% [1/76] and 24% [9/38] vs 28% [21/76], respectively). Severe cerebral injury was detected in 1 infant (5%) in the TAPS group and 1 infant (2%) in the control group. CONCLUSION: Neonatal mortality and morbidity rates in a select population of TAPS neonates are similar to control neonatal rates.
Enrico Lopriore; Femke Slaghekke; Dick Oepkes; Johanna M Middeldorp; Frank P Vandenbussche; Frans J Walther
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Publication Detail:
Type:  Journal Article     Date:  2010-04-24
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  203     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-09-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  54.e1-5     Citation Subset:  AIM; IM    
Copyright Information:
Copyright (c) 2010 Mosby, Inc. All rights reserved.
Division of Neonatology, Department of Pediatrics, Leiden University Medical Centre, Leiden, the Netherlands.
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MeSH Terms
Anemia / blood,  pathology*,  therapy
Blood Transfusion
Brain Injuries / pathology,  ultrasonography
Cohort Studies
Fetofetal Transfusion / blood,  pathology*,  therapy
Hemoglobins / metabolism
Infant Mortality
Infant, Newborn
Laser Coagulation
Polycythemia / blood,  pathology*,  therapy
Reticulocyte Count
Twins, Monozygotic
Reg. No./Substance:

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