| Clinical outcome of 193 extracardiac Fontan patients: the first 15 years. | |
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MedLine Citation:
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PMID: 16697327 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: We sought to evaluate the mid-term outcome of hospital survivors with extracardiac Fontan circulation. BACKGROUND: Few data exist about the mid-term and long-term results of the extracardiac Fontan operation. METHODS: From November 1988 to November 2003, 221 patients underwent an extracardiac Fontan procedure as primary (9 patients) or secondary (212 patients) palliation, at a mean age of 72.2 months (range 13.1 to 131.3 months). A total of 165 of 193 early survivors underwent programmed noninvasive follow-up evaluations and at least one cardiac catheterization. RESULTS: The overall survival, including operative deaths, was 85% at 15 years. Freedom from late failure among hospital survivors is 92% at 15 years. A total of 127 of 165 survivors (77%) were in New York Heart Association functional class I. The incidence of late major problems was 24% (42 major problems in 36 of 165 patients): 19 patients had arrhythmias (11%), 5 patients had obstruction of the extracardiac conduit (3%) and 6 of the left pulmonary artery (3.5%), and 5 patients experienced ventricular failure (3%), leading to heart transplantation in 3 patients. Protein-losing enteropathy was found in two patients (1%). The incidence of late re-interventions was 12.7% (21 of 165 patients, including 15 epicardial pacemaker implantations). Four patients died (2.3%), two after heart transplantation. CONCLUSIONS: After 15 years of follow-up, the overall survival, the functional status, and the cardiopulmonary performance of survivors of the extracardiac Fontan procedure compare favorably with other series of patients who underwent the lateral tunnel approach. The incidence of late deaths, obstructions of the cavopulmonary pathway, re-interventions, and arrhythmias is lower than that reported late after other Fontan-type operations. |
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Authors:
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Salvatore Giannico; Fatma Hammad; Antonio Amodeo; Guido Michielon; Fabrizio Drago; Attilio Turchetta; Roberto Di Donato; Stephen P Sanders |
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Publication Detail:
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Type: Journal Article Date: 2006-04-27 |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 47 ISSN: 1558-3597 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 2006 May |
Date Detail:
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Created Date: 2006-05-15 Completed Date: 2006-05-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 2065-73 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatric Cardiology and Cardiac Surgery, Rome, Italy. s.giannico@opbg.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiovascular Diseases
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etiology,
surgery Cardiovascular Surgical Procedures Child Child, Preschool Exercise Test Exercise Tolerance Follow-Up Studies Fontan Procedure* / adverse effects Heart Defects, Congenital / surgery* Humans Infant Pulmonary Artery / surgery Recovery of Function Reoperation Respiratory Function Tests Survival Analysis Treatment Outcome Vascular Patency Vena Cava, Inferior / surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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