Document Detail


Clinical-neuroendocrinological syndromes due to lesions of the cingulate gyrus in humans.
MedLine Citation:
PMID:  9850954     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clinical and neuroendocrinological studies were performed in 41 patients with arteriovenous malformations (AVM) of the cingulate gyrus. Before surgery, the primary affliction in 38 patients consisted of memory disturbance, 5 of these having signs of Korsakov's syndrome. Autonomic and epileptic fits were not typical. Of 38 patients undergoing surgery, postoperative worsening of memory occurred in 23, but no qualitatively new disturbances appeared. Korsakov's syndrome appeared de novo after surgery in 3 patients. The extent of memory disturbances correlated with the extent of lesions to the cingulate gyrus and with the extent to which AVM affected the corpus callosum. Qualitative analysis of memory loss syndromes revealed alterations in trace selectivity in nearly all patients and failure to retain the meaning of stories, which was accompanied by lack of insight into the patients' abnormalities. The signs of these syndromes showed clear similarity with memory deficiencies in patients with frontal lesions. This suggests that not only the frontal lobes themselves, but also their connections, are involved in producing the clinical picture in humans.
Authors:
S B Buklina
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Neuroscience and behavioral physiology     Volume:  28     ISSN:  0097-0549     ISO Abbreviation:  Neurosci. Behav. Physiol.     Publication Date:    1998 Nov-Dec
Date Detail:
Created Date:  1999-03-15     Completed Date:  1999-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0330471     Medline TA:  Neurosci Behav Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  601-7     Citation Subset:  IM    
Affiliation:
N. N. Burdenko Science Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cerebrovascular Circulation / physiology
Child
Endocrine System Diseases / etiology*,  physiopathology,  psychology
Female
Gyrus Cinguli / abnormalities*,  blood supply,  surgery
Humans
Intracranial Arteriovenous Malformations / physiopathology*,  psychology
Male
Memory Disorders / physiopathology
Middle Aged
Nervous System Diseases / etiology*,  physiopathology,  psychology
Neuropsychological Tests
Neurosurgical Procedures
Psychomotor Performance
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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