Document Detail


Clinical manifestations and outcomes of parvovirus B19 infection during pregnancy in Japan.
MedLine Citation:
PMID:  16864949     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Parvovirus B19 is a small DNA virus. Infection with parvovirus B19 during pregnancy may cause serious complications in the fetus, including hydrops fetalis and fetal death. The purpose of the present study is to clarify the clinical manifestations and outcomes of parvovirus B19 infection during pregnancy. This prospective study enrolled 478 women with suspected B19 infections during pregnancy between 1999 and 2004. One hundred cases (21%) of B19 infection were detected in 478 pregnant women who had been exposed to B19. Serological infection was confirmed by measurement of B19-specific IgM and IgG in sera. Forty-nine cases reported maternal clinical symptoms and 51 cases were asymptomatic. Facial rash was the most common symptom, with 51% (25/49) of the symptomatic patients complaining of either a facial, body or limb rash. The most common infectious source was children living in the home. Overall, the incidence of adverse fetal effects (including hydrops fetalis and fetal death) related to intrauterine B19 infection was 7% (7/100), and all seven cases were exposed to B19 infection before 20 weeks of gestation. Although half of the cases with parvovirus B19 infections during pregnancy were asymptomatic, patients with adverse fetal effects tended to be symptomatic including rash and fever. These clinical data may supply useful information to produce clinical guidelines for managing B19 infection during pregnancy.
Authors:
Hiroshi Chisaka; Kiyoshi Ito; Hitoshi Niikura; Jun-ichi Sugawara; Tadao Takano; Takashi Murakami; Yukihiro Terada; Kunihiro Okamura; Hiroyuki Shiroishi; Kazuo Sugamura; Nobuo Yaegashi
Related Documents :
11241539 - Fetal varicella-herpes zoster syndrome in early pregnancy: ultrasonographic and morphol...
9859959 - Maternal and perinatal factors related to maternal-infant transmission of hiv-1 in the ...
17566949 - Idiopathic vertebral abscess in pregnancy: case report and literature review.
17505669 - Detection of parvovirus b19 infection in formalin-fixed and paraffin-embedded placenta ...
22182369 - Spontaneous procreation in turner syndrome: report of two pregnancies in the same patient.
23479309 - Assessment of the fetal heart at 12-14 weeks of pregnancy using b-mode, color doppler,...
17207339 - High rate of biological loss in assisted reproduction: it is in the seed, not in the soil.
17355899 - Real life is different: a qualitative study of why women delay abortion until the secon...
16790099 - Obesity and assisted reproductive technology outcomes.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  209     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-25     Completed Date:  2006-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  277-83     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous / epidemiology,  virology
Female
Humans
Japan
Parvoviridae Infections / epidemiology,  physiopathology*
Parvovirus B19, Human* / immunology
Pregnancy
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Documented subacute stent thrombosis within thirty days after stenting with sirolimus-eluting stent ...
Next Document:  Early effects of percutaneous mitral valvuloplasty on left atrial mechanical functions.