Document Detail

Clinical manifestation and survival of patients with non-small cell lung cancer.
MedLine Citation:
PMID:  15222519     Owner:  NLM     Status:  MEDLINE    
A retrospective study of clinical manifestations and survival of patients with non-small cell lung cancer (NSCLC) in Sonklanagarind Hospital between 1995-98 was undertaken. There were 209 evaluable NSCLC patients enrolled in the study. NSCLC was common in elderly men who smoked. Major symptoms were cough 74.9%, weight loss 61.6% and dyspnea 54.6%. Chest pain and hemoptysis were presented in only 31.3% and 29.2% respectively. Adenocarcinoma was found in 109 patients (52.1%) , squamous cell carcinoma in 71 patients (34.0%), and large cell carcinoma in 8 patients (3.8%). Only 28 patients (13.4%) were in stage I or II. Surgery was performed in 18 cases (8.6%). Radiation for palliative treatment was used in 74 cases (35.4%). Fifty-four patients (25.8%) received chemotherapy. Forty-two patients received mitomycin, vinblastine and cisplatin regimen (MVP). The response to treatment comprised 3 cases (7.1%) with complete response, and 9 cases (21.4%) with partial response. The survival of the patients in stages I and II was lower than reported from Western countries but in stages III and IV the survival was comparable. Chemotherapy tended to improve survival in advanced stage NSCLC.
Kreetha Thammakumpee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  87     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-06-29     Completed Date:  2004-08-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  503-7     Citation Subset:  IM    
Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat-Yai, Songkhla, Thailand.
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MeSH Terms
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung / complications*,  diagnosis,  mortality*,  therapy
Lung Neoplasms / complications*,  diagnosis,  mortality*,  therapy
Middle Aged
Retrospective Studies
Survival Rate
Thailand / epidemiology

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