| Clinical laboratory investigation of the Sanofi ACCESS CK-MB procedure and comparison to electrophoresis and Abbott IMx. | |
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MedLine Citation:
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PMID: 8701919 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This evaluation was undertaken to verify the application protocol for the CK-MB assay on the ACCESS Immunoassay Analyzer (Sanofi Diagnostics Pasteur, Chaska, MN). The results show that the ACCESS CK-MB assay total imprecision was 6.8% to 9.1%. Analytical linearity of the ACCESS CK-MB assay was excellent in the range of < 1-214 micrograms/L. A comparison of the ACCESS CK-MB assay with the IMx (Abbott Laboratories, Abbott Park, IL) method shows good correlation r = 0.990 (n = 108). Linear regression analysis yielded Y = 1.36X-0.3, Sx/y = 7.2. ACCESS CK-MB values also correlated well with CK-MB by electrophoresis with r = 0.968 (n = 132). The linear regression equation for this comparison was Y = 1.08X + 1.4, Sx/y = 14.1. The expected non-myocardial infarction range of CK-MB determined by the ACCESS system was 1.3-9.4 micrograms/L (mean = 4.0, n = 58). The ACCESS CK-MB assay would appear to be rapid, precise and clinically useful. |
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Authors:
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G D Mao; K Adeli; A B Eisenbrey; J D Artiss |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of clinical pathology Volume: 106 ISSN: 0002-9173 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 1996 Jul |
Date Detail:
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Created Date: 1996-09-05 Completed Date: 1996-09-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 112-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Chemistry and Biochemistry, University of Windsor, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Blood Protein Electrophoresis / methods*, standards Calibration Creatine Kinase / blood*, standards Female Humans Immunoenzyme Techniques* / standards Isoenzymes Male Middle Aged Reagent Kits, Diagnostic* / standards Reproducibility of Results Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Isoenzymes; 0/Reagent Kits, Diagnostic; EC 2.7.3.2/Creatine Kinase |
| Comments/Corrections | |
Comment In:
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Am J Clin Pathol. 1997 May;107(5):619-20
[PMID:
9128277
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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