| Clinical and laboratory diagnosis of hemostatic disorders in newborn infants. | |
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MedLine Citation:
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PMID: 543515 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a microtechnology for the study of the coagulation system in newborn infants. Interpretation of results demands an understanding of the techniques used and the nature of the control population from which normal values are drawn. We have examined two syndromes which represent the majority of hemostatic disorders of sick newborn infants. The first is thrombocytopenia resulting from bacterial infections in which there are minimal changes in the levels of blood coagulation factors and little tendency to bleed. The second is a syndrome of disseminated intravascular coagulation in which there is a profound disturbance in the coagulation mechanism, relatively little change in platelet counts, a severe hemorrhagic diathesis, and widespread ischemic necrosis. |
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Authors:
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A Zipursky; D deSa; E Hsu; M Johnston; R Milner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of pediatric hematology/oncology Volume: 1 ISSN: 0192-8562 ISO Abbreviation: Am J Pediatr Hematol Oncol Publication Date: 1979 |
Date Detail:
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Created Date: 1980-06-25 Completed Date: 1980-06-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7908071 Medline TA: Am J Pediatr Hematol Oncol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 217-26 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bacterial Infections
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complications Blood Coagulation Factors / analysis Disseminated Intravascular Coagulation / diagnosis*, etiology Heart Arrest / complications Hemorrhagic Disorders / etiology Hemostasis Humans Infant, Newborn Infant, Newborn, Diseases / diagnosis*, etiology Prothrombin Time Shock, Hemorrhagic / complications Thrombocytopenia / diagnosis*, etiology |
| Chemical | |
Reg. No./Substance:
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0/Blood Coagulation Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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