| Clinical indicators for pulmonary arterial hypertension in thalassemia. | |
| | |
MedLine Citation:
|
PMID: 22379736 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
OBJECTIVE: To explore clinical indicators for pulmonary arterial hypertension (PAH) in thalassemia (Thal). MATERIAL AND METHOD: A study was conducted in thalassemia patients at Chiang Rai Hospital, Chiang Rai, Thailand. Pulmonary artery systolic pressure (PASP) was determined by doppler echocardiography and PAH was defined as PASP > 35 mmHg. Patient characteristics were extracted from medical records. Characteristics of patients with and without PAH were compared. Risk indicators were explored with logistic regression analysis. RESULTS: Two hundred twenty four patients were included, 144 E/beta-Thal, 37 homozygous beta-Thal and 43 Hb H disease. There were 65 patients (29.0%) with PAH, 53 (81.5%) with E/beta-Thal, 8 (12.3%) with homozygous beta-Thal and 4 (6.2%) with Hb H disease. In a multivariable analysis, features significantly associated with PAH were E/beta-Thal (OR = 1.98, 95% CI; 1.29-3.01) and post splenectomy status (OR = 2.36, 95% CI; 1.17-4.73). CONCLUSION: Significant indicators for PAH in thalassemia were E/beta-Thal and post splenectomy status. |
| | |
Authors:
|
Nonlawan Chueamuangphan; Wattana Wongtheptien; Weerasak Nawarawong; Apichard Sukornthasarn; Suporn Chuncharunee; Chamaiporn Tawichasri; Jayanton Patumanond |
Related Documents
:
|
21967326 - Congenitally corrected transposition of the great arteries with anomalous inferior vena... 12901816 - Unusual complication of ingestion of a foreign body. 18465036 - Transarterial embolisation of spontaneous adrenal pheochromocytoma rupture using polyvi... 3998756 - Hyperkalaemic paralysis following traumatic rupture of the urinary bladder. 19168826 - Cerebral sinus venous thrombosis complicated by cerebellar hemorrhage in a child with a... 15495166 - Unusual insertion of the coracobrachialis muscle to the brachial fascia associated with... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of the Medical Association of Thailand = Chotmaihet thangphaet Volume: 95 ISSN: 0125-2208 ISO Abbreviation: J Med Assoc Thai Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-03-02 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7507216 Medline TA: J Med Assoc Thai Country: Thailand |
Other Details:
|
Languages: eng Pagination: 16-21 Citation Subset: IM |
Affiliation:
|
Department of Medicine, Chiang Rai Hospital, Chiang Rai, Thailand. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The prevalence of hepatitis B in premarital counseling clinic at Siriraj Hospital.
Next Document: Role of clinical parameters for predicting the cause of upper gastrointestinal bleeding.