Document Detail

Clinical improvement precedes lesion size regression in a severe case of acute disseminated encephalomyelitis.
MedLine Citation:
PMID:  23175006     Owner:  NLM     Status:  In-Data-Review    
Here, we present a case of a severe acute disseminated encephalomyelitis (ADEM) of a 42-year-old male patient. The diagnosis was established after brain biopsy and due to acutely evolving encephalopathy occurring in the context of atypical Mycoplasma pneumoniae (MP). We analysed the prominent MRI white matter lesions using a three-dimensional algorithm as cutting-edge technique to study morphological abnormalities and correlated them to the clinical condition of the patient. We found a discrepancy between the lesion size and the clinical deficits of the patient, actually the clinical improvement antedated the regression of the white matter lesions.
Mark Stettner; Philipp Albrecht; Angelika Derksen; Christian Hartmann; Bernd Turowski; Eva Neuen-Jacob; Hans Peter Hartung; Bernd C Kieseier; Gabriele Arendt
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Publication Detail:
Type:  Journal Article     Date:  2012-11-21
Journal Detail:
Title:  BMJ case reports     Volume:  2012     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2012  
Date Detail:
Created Date:  2012-11-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Department of Neurology, Medical Faculty Heinrich-Heine-University, Düsseldorf, Germany.
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