Document Detail

Clinical importance of impedance measurements.
MedLine Citation:
PMID:  18364586     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Because impedance changes have been shown to be a sensitive and reliable means to detect fluid or gas movement within the esophagus, numerous studies worldwide have addressed the potential for impedance determinations to provide a sensitive measure of either esophageal transit function or the presence and extent of gastroesophageal reflux. Using a catheter with multiple impedance measuring sites [multichannel intraluminal impedance (MII)] allows the opportunity to track fluid movement within the esophagus. AIM: To review the clinical importance of impedance measurements. CONCLUSIONS: Ambulatory MII-pH monitoring is a valuable tool in the assessment of reflux because it identifies not only acid reflux but overcomes the deficiency of simple pH monitoring by showing all reflux types, both acid and nonacid. It is our belief that MII-pH testing on proton pump inhibitor therapy has become the new "gold standard" for detection of reflux and for clarifying its relationship to symptoms.
Amit Agrawal; Donald O Castell
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of clinical gastroenterology     Volume:  42     ISSN:  0192-0790     ISO Abbreviation:  J. Clin. Gastroenterol.     Publication Date:    2008 May-Jun
Date Detail:
Created Date:  2008-04-22     Completed Date:  2008-08-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7910017     Medline TA:  J Clin Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  579-83     Citation Subset:  IM    
Digestive Diseases Center, Medical University of South Carolina, Charleston, SC 29425, USA.
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MeSH Terms
Electric Impedance / diagnostic use*
Equipment Design
Esophagus / physiopathology*
Gastroesophageal Reflux / diagnosis*,  physiopathology
Severity of Illness Index

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