| Clinical implications of skeletal muscle blood-oxygenation-level-dependent (BOLD) MRI. | |
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MedLine Citation:
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PMID: 22374263 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Blood-oxygenation-level-dependent (BOLD) contrast in magnetic resonance (MR) imaging of skeletal muscle mainly depends on changes of oxygen saturation in the microcirculation. In recent years, an increasing number of studies have evaluated the clinical relevance of skeletal muscle BOLD MR imaging in vascular diseases, such as peripheral arterial occlusive disease, diabetes mellitus, and chronic compartment syndrome. BOLD imaging combines the advantages of MR imaging, i.e., high spatial resolution, no exposure to ionizing radiation, with functional information of local microvascular perfusion. Due to intrinsic contrast provoked via changes in hemoglobin oxygen saturation, it is a safe and easy applicable procedure on standard whole-body MR devices. Therefore, BOLD MR imaging of skeletal muscle is a potential new diagnostic tool in the clinical evaluation of vascular, inflammatory, and muscular pathologies. Our review focuses on the current evidence concerning the use of BOLD MR imaging of skeletal muscle under pathological conditions and highlights ways for future clinical and scientific applications. |
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Authors:
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Sasan Partovi; Sasan Karimi; Bjoern Jacobi; Anja-Carina Schulte; Markus Aschwanden; Lisa Zipp; John K Lyo; Christof Karmonik; Matthias Müller-Eschner; Rolf W Huegli; Georg Bongartz; Deniz Bilecen |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-29 |
Journal Detail:
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Title: Magma (New York, N.Y.) Volume: - ISSN: 0968-5243 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9310752 Medline TA: MAGMA Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, University Hospital Bruderholz, 4101 Bruderholz, Basel, Switzerland, sasanp@gmx.de. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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