| Clinical implementation of enhanced dynamic wedges into the Pinnacle treatment planning system: Monte Carlo validation and patient-specific QA. | |
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MedLine Citation:
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PMID: 19098353 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The goal of this work is to present a systematic Monte Carlo validation study on the clinical implementation of the enhanced dynamic wedges (EDWs) into the Pinnacle(3) (Philips Medical Systems, Fitchburg, WI) treatment planning system (TPS) and QA procedures for patient plan verification treated with EDWs. Modeling of EDW beams in the Pinnacle(3) TPS, which employs a collapsed-cone convolution superposition (CCCS) dose model, was based on a combination of measured open-beam data and the 'Golden Segmented Treatment Table' (GSTT) provided by Varian for each photon beam energy. To validate EDW models, dose profiles of 6 and 10 MV photon beams from a Clinac 2100 C/D were measured in virtual water at depths from near-surface to 30 cm for a wide range of field sizes and wedge angles using the Profiler 2 (Sun Nuclear Corporation, Melbourne, FL) diode array system. The EDW output factors (EDWOFs) for square fields from 4 to 20 cm wide were measured in virtual water using a small-volume Farmer-type ionization chamber placed at a depth of 10 cm on the central axis. Furthermore, the 6 and 10 MV photon beams emerging from the treatment head of Clinac 2100 C/D were fully modeled and the central-axis depth doses, the off-axis dose profiles and the output factors in water for open and dynamically wedged fields were calculated using the Monte Carlo (MC) package EGS4. Our results have shown that (1) both the central-axis depth doses and the off-axis dose profiles of various EDWs computed with the CCCS dose model and MC simulations showed good agreement with the measurements to within 2%/2 mm; (2) measured EDWOFs used for monitor-unit calculation in Pinnacle(3) TPS agreed well with the CCCS and MC predictions within 2%; (3) all the EDW fields satisfied our validation criteria of 1% relative dose difference and 2 mm distance-to-agreement (DTA) with 99-100% passing rate in routine patient treatment plan verification using MapCheck 2D diode array. |
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Authors:
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Munir Ahmad; Jun Deng; Molly W Lund; Zhe Chen; James Kimmett; Meena S Moran; Ravinder Nath |
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Publication Detail:
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Type: Journal Article; Validation Studies Date: 2008-12-19 |
Journal Detail:
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Title: Physics in medicine and biology Volume: 54 ISSN: 0031-9155 ISO Abbreviation: Phys Med Biol Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2008-12-22 Completed Date: 2009-03-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 447-65 Citation Subset: IM |
Affiliation:
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Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA. munir.ahmad@yale.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biophysical Phenomena Humans Models, Theoretical Monte Carlo Method Particle Accelerators Phantoms, Imaging Quality Assurance, Health Care Radiotherapy Planning, Computer-Assisted / methods*, standards, statistics & numerical data Radiotherapy, Conformal / methods, standards, statistics & numerical data Radiotherapy, High-Energy / methods, standards, statistics & numerical data Scattering, Radiation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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